Question 1

What is Stoke Therapeutics' mission?

Accepted Answer

Stoke Therapeutics' mission is to boldly restore genetic health by restoring protein expression through their proprietary TANGO platform, which aims to increase protein output from healthy genes to compensate for non-functioning copies.

Question 2

What is the TANGO platform?

Accepted Answer

The TANGO (Targeted Augmentation of Nuclear Gene Output) platform is Stoke Therapeutics' proprietary research platform that aims to restore missing proteins by increasing protein output from healthy genes, compensating for the non-functioning copy of the gene.

Question 3

What types of diseases is Stoke Therapeutics targeting?

Accepted Answer

Stoke Therapeutics is initially focusing on diseases where one copy of a gene functions normally and the other is mutated, also known as haploinsufficiencies. The company is currently working on Dravet syndrome, ADOA, Rett syndrome, and SYNGAP

Question 4

What clinical studies is Stoke Therapeutics conducting?

Accepted Answer

Stoke Therapeutics encourages patients and families to visit their clinical studies page to learn about the ongoing and upcoming clinical studies for their various disease areas.

Question 5

What career opportunities are available at Stoke Therapeutics?

Accepted Answer

Stoke Therapeutics offers a variety of career opportunities, including job openings in research, clinical development, operations, and more. The company also highlights its commitment to diversity, inclusion, and belonging.

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What is Stoke Therapeutics' mission?

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What types of diseases is Stoke Therapeutics targeting?

What clinical studies is Stoke Therapeutics conducting?

What career opportunities are available at Stoke Therapeutics?

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